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1-Fluoronaphthalene


1-Fluoronaphthalene with the CAS number 321-38-0 under the brand name Malpanol FN. We are manufacture and export of this product used as a pharmaceutical intermediate. Its similar names are α-Fluoronaphthalene; Duloxetine USP Impurity G; Duloxetine EP Impurity G.

1-Fluoronaphthalene

Technical Data Sheet of 1-Fluoronaphthalene

Revision No.: 1

Revision Date: 11 / 2018

PRODUCT DESCRIPTION

Product Name 1-Fluoronaphthalene
Molecular Formula C10H7F
Molecular Weight 146.16g/mol
CAS No 321-38-0

* 1-Fluoronaphthalene is a fluorinated naphthalene derivative that is metabolized by fungal monooxygenase-epoxide hydrolase.

Synonyms

α-Fluoronaphthalene; Duloxetine USP Impurity G; Duloxetine EP Impurity G; 4-fluoro-l-naphthalene; I-Fluoronaphthalene; 1-FLUORONAPTHALENE; 1-fluoromaphthalene; 1-fluoro-naphthalen; Naphthalene, 1-fluoro-; 1-FLUORONAPHTHALENE; I-Fluornaphthalin; 1-Fluornaftalen; NSC 4690; 1-Fluoronaphthalene, 99%; Naphthalene, fluoro-; CAS 321-38-0.


SPECIFICATION

Appearance Clear colorless liquid
Odour Product specific
Purity 98%
Density 1.331g/cm3
PH value Data not available
Boiling Point 215-217°C
Melting Point -10°C
Flash Point 65ºC
Refractive Index 1.593
Solubility Slightly soluble in water, well soluble in Chloroform, Ethyl Acetate, and Methanol.
Stability Stable under recommended storage conditions.

STRUCTURAL FORMULA: 1-Fluoronaphthalene




MAJOR APPLICATIONS

1-Fluoronaphthalene is used in t-BuLi-mediated synthesis of 6-substituted phenanthridines. It is also used as a pharmaceutical intermediate.
1-Fluoronaphthalene is a fluorinated naphthalene derivative that is metabolized by fungal monooxygenase-epoxide hydrolase.
1-Fluoronaphthalene was used for the tert-butyllithium-mediated synthesis of 6-substituted phenanthridines.
It has also been used in the synthesis of LY248686, a potent inhibitor of serotonin and norepinephrine uptake.

STORAGE CONDITION

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

PACKING

Metal or HDPE drums packaging (we can package depending upon customer requirements, e.g. 25, 50 or 200kg).

Industrial References

Note: Information given in this technical data sheet is based on current knowledge and our laboratory evaluation; it is presented as per our opinion without any guarantee. Buyers must carry out their own tests and experiments to determine the suitability and completeness of our products for their use and application.

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